COURSE: Immunology
COURSE NUMBER: BIOT 2352
INSTRUCTOR: Ron Scribner
PHONE: (405) 682-1611, ext. 7360
______________________________________________________________
COURSE DESCRIPTION
Prerequisite: BIO 2125
The student will discuss the nonspecific and specific immune systems of
the human organism. Course topics will include antigen-antibody interactions,
cell-mediated immunity, interferon, natural killer cells, and complement.
2 credits.
COURSE PACING
BIOT 2352 is a group-paced course. Your instructors will establish testing
and assignment dates. These dates must be observed in order to maintain
good standing in the class.
COURSE GRADING CRITERIA
A: 90-100% average
B: 80-89% average
C: 70-79% average
D: 65-69% average
F: Below 65% average
Grades will be based on your performances on a combination of classroom
tests, presentations, and assignments.
SOURCE OF CRITERIA
The objectives and competency levels for this course are based upon the
professional judgment of Biotechnology faculty and upon comparable courses
from other institutions of higher education.
LEARNING RESOURCES
How the Immune System Works, L. Sompayrac,
Blackwell Science, 1999.
ATTENDANCE POLICY:
You are expected to attend and actively participate in all scheduled classes
for this course.
ACCOMMODATIONS FOR STUDENTS WITH SPECIAL NEEDS
Oklahoma City Community College complies with Section 504 of the Rehabilitation
Act of 1973 and the American with Disabilities Act of 1990. Students with
disabilities who need accommodations should make their request in the following
ways:
· Talk with your instructor after class or during office hours about
your disability or special needs related to work in class, AND
· Complete the Services to Students with Disabilities Intake/Referral
Form provided in the Office of Services to Students With Disabilities (unless
this has been completed).
· For additional information, call 682-7250 V/TTY
COURSE OBJECTIVES
1. Define innate and acquired immunity.
2. Discuss the three lines of defense of the human body.
3. Discuss the physical and chemical barriers which help prevent infection.
4. Discuss phagocytosis and inflammation.
5. List and give characteristics of components of blood.
6. Describe the function of the lymphatic system.
7. Discuss the function of granulocytes and agranulocytes.
8. Discuss the characteristics of antigens.
9. Discuss the origin of the immune system.
10. Give an overview of the function of cellular and humoral immunity.
11. Discuss structure and function of immunoglobulins.
12. Compare five immunoglobulin classes.
13. Discuss primary and anamnestic antibody responses.
14. Discuss clonal selection theory of antibody production.
15. Discuss monoclonal antibodies.
16. Discuss cytokines.
17. Discuss complement.
18. Discuss natural killer (NK) cells, cytotoxic T-cell (Tc), and lymphokine
activated killer (LAK) cells.
19. Discuss the major histocompatability complex (MHC) and its role
in antigen presentation, and in transplantation immunology, and histocompatability
screening.
20. Discuss experimental systems used in immunological research.
21. Discuss autografts, isografts, allografts, and xenografts.
22. Discuss bone marrow transplantation and the graft versus host reaction.
23. Discuss antirejection mechanisms.
24. Characterize the different types of acquired immunity.
25. Discuss the four generations of vaccines presently available and
certain experimental approaches to immunization.
26. Define serology, and dicuss its role in diagnosis; characterize
various serological tests.
27. Discuss four types of hypersensitivity as defined byGell and Coombs
and give examples of autoimmune diseases.
28. Describe the following immune deficiency diseases: agammaglobulinemia,
hypogammaglobulinemias, cell mediated defects including DiGeorge's Syndrome,
severe combined immune deficiency syndrome (SCID) including X-linked
and adenosine deaminase deficiency (ADA), AIDS, Chediak-Higashi Syndrome,
chronic granulomatous disease (CGD).
29. Discuss transformed human cells and characterize the role of the
immune system in tumor immunology.
30. Describe immunotherapy modalities presently in use.
31. Discuss immunity to infectious diseases.
Oklahoma City Community College Biotechnology Program
Dr. Fabiola Janiak-Spens, Program Director
7777 S. May Avenue
Oklahoma City, OK 73159-4444
(405) 682-1611, ext 7414
Comments: Cmulvihill@okccc.edu
Copyright
1998 Oklahoma City Community College
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